Download Applications of Transition Metal Catalysis in Drug Discovery by Matthew L. Crawley, Barry M. Trost PDF

By Matthew L. Crawley, Barry M. Trost

This e-book specializes in the drug discovery and improvement purposes of transition steel catalyzed techniques, which could successfully create preclinical and medical drug applicants in addition to advertised drugs.  The authors pay specific cognizance to the demanding situations of transitioning academically-developed reactions into scalable business tactics. also, the booklet lays the foundation for a way endured improvement of transition steel catalyzed techniques can convey new drug applicants. This paintings offers a special point of view at the functions of transition steel catalysis in drug discovery and improvement – it's a advisor, a historic potential, a pragmatic compendium, and a resource of destiny course for the sphere

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By Matthew L. Crawley, Barry M. Trost

This e-book specializes in the drug discovery and improvement purposes of transition steel catalyzed techniques, which could successfully create preclinical and medical drug applicants in addition to advertised drugs.  The authors pay specific cognizance to the demanding situations of transitioning academically-developed reactions into scalable business tactics. also, the booklet lays the foundation for a way endured improvement of transition steel catalyzed techniques can convey new drug applicants. This paintings offers a special point of view at the functions of transition steel catalysis in drug discovery and improvement – it's a advisor, a historic potential, a pragmatic compendium, and a resource of destiny course for the sphere

Show description

Read or Download Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective PDF

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Chem. Soc. 2000, 122, 8168. ; Stevens, E. ; Nolan, S. ; Peterson, J. L. J. Am. Chem. Soc. 1999, 121, 2674. ; Grela, K. J. Am. Chem. Soc. 2004, 126, 9318. [89] Schrock, R. , Murdzek, J. ; Bazan, G. ; O’Regan, M. J. Am. Chem. Soc. 1990, 112, 3875. -Y. S. Patent 0043180 (2007). ; Yee, N. ; Busacca, C. ; Senanayake, C. H. Org. Lett. ; Yee, N. ; Senanayake, C. H. Org. Process Res. Dev. 2009, 13, 250. [92] Burgey, C. ; Paone, D. ; Shaw, A. ; Deng, J. ; Nguyen, D. ; Potteiger, C. , Vacca, J. ; Williams, T.

Org. Chem. -C. Angew. Chem. Int. Ed. 2011, 50, 1896. ; Engle, K. -Q. Angew. Chem. Int. Ed. 2009, 48, 5094; (b) Peng, H. ; You, S. L. Angew. Chem. Int. Ed. ; Gorelsky, S. ; Chung, B. K. ; Fagnou, K. J. Am. Chem. Soc. 2010, 132, 10692. ; Lassaletta, J. M. J. Am. Chem. Soc. ; Jones, G. ; Watson, D. ; Buchwald, S. L. J. Am. Chem. Soc. 2010, 132, 11278. [31] LaPlante, S. ; Edwards, P. ; Fader, L. ; Hucke, O. Chem. Med. Chem. 2011, 6, 505. [32] (a) For a selected review, see: Glorius, F. Angew. Chem.

Synthesis 2008, 1647. ; Shibasaki, M. J. Am. Chem. Soc. ; Shibasaki, M. J. Am. Chem. Soc. 2010, 132, 6638. REFERENCES 23 [83] Fandrick, D. ; Fandrick, K. ; Reeves, J. ; Capacci, A. ; Song, J. ; Yee, N. ; Senenayake, C. H. J. Am. Chem. Soc. 2010, 132, 7600. [84] Ivin, K. ; Mol, J. C. Olefin Metathesis and Metathesis Polymerisation; Academic Press: San Diego, 1997. ; Lee, S. ; Grubbs, R. H. Org. Lett. 1999, 1, 953. [86] Garber, S. ; Kingsbury, J. ; Gray, B. ; Hoveyda, A. H. J. Am. Chem. Soc. 2000, 122, 8168.

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