By Yitzhak Rosen, Noel Elman
"This booklet is vital while designing, constructing and learning biomedical materials.… presents an outstanding review—from a sufferer, sickness, or even genetic element of view—of fabrics engineering for the biomedical box. … This good awarded booklet strongly insists on how the fabrics can impression sufferers’ wishes, the final word force for biomedical engineering. …[presents an] fascinating and cutting edge overview from a sufferer concentration perspective—the e-book emphasizes the significance of the sufferers, which isn't frequently coated in different biomedical material’s books."
—Fanny Raisin-Dadre, BioInteractions Ltd., Berkshire, England
Going a ways past the insurance in most traditional books at the subject, Biomaterials technology: An built-in scientific and Engineering Approach bargains an exceptional evaluate of using biomaterials in scientific units, drug supply, and tissue engineering.
Combining dialogue of fabrics technological know-how and engineering views with scientific facets, this publication emphasizes integration of medical and engineering methods. particularly, it explores quite a few purposes of biomaterials in fields together with tissue engineering, neurosurgery, hemocompatibility, BioMEMS, nanoparticle-based drug supply, dental implants, and obstetrics/gynecology.
The e-book engages these engineers and physicians who're making use of biomaterials at numerous degrees to:
- Increase the speed of winning deployment of biomaterials in humans
- Lower the side-effects of this kind of deployment in humans
- Accumulate wisdom and event for bettering present methodologies
- Incorporate details and knowing appropriate to destiny demanding situations, similar to everlasting synthetic organ transplants
Using a number of members from either the medical and engineering facets of the fields pointed out above, this ebook stands aside by way of emphasizing a necessity for the customarily missing strategy that integrates those both vital features.
Read or Download Biomaterials Science: An Integrated Clinical and Engineering Approach PDF
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Extra resources for Biomaterials Science: An Integrated Clinical and Engineering Approach
Chronic arterial-wall inflammation and endothelial dysfunction may be associated with the increased rate of target vessel revascularization at a late stage, which has been found particularly in patients with complex lesions, including those with diabetes [24, 25]. Among the biodegradable polymers implemented, polylactic acid, polyglycolide, and poly(D,L-lactic-co-glycolic acid) are particularly common. These can be completely metabolized as they break into monomers, water, and carbon dioxide. Stents with these biodegradable polymers have antiproliferative agents as eluting agents, which include sirolimus, tacrolimus, biolimus, and paclitaxel [27, 51–60].
Effectiveness of paclitaxel-eluting balloon catheter in patients with sirolimus-eluting stent restenosis. JACC Cardiovasc Interv 4(2): 149–54. 76. Erne P, Schier M, Resink TJ. 2006. The road to bioabsorbable stents: Reaching clinical reality? Cardiovasc Intervent Radiol 29: 11–6. 77. Baber U, Kini AS, Sharma SK. 2010. Stenting of complex lesions: An overview. Nat Rev Cardiol. Sep, 7(9):485–96. 78. Aoki J, Ong AT, Rodriguez Granillo GA, et al. 2005. “Full metal jacket” (stented length > or = 64 mm) using drug-eluting stents for de novo coronary artery lesions.
The alloy 316L has been considered a standard reference for mechanical properties related to new biomaterials for various stent applications [51–60]. An important clinical use for the bioabsorbable Mg-based stent has been in pediatrics. A successful implantation of such a stent into the left pulmonary Principles of Clinical and Engineering Integration in Hemocompatibility 21 artery of a preterm baby allowed the reperfusion of the left lung. The reperfusion persisted throughout the 4-month follow-up period during the degradation process of the stent until it was completed.