Download Book MRI in Ischemic Stroke by Rüdiger von Kummer, Tobias Back, K. Sartor PDF

By Rüdiger von Kummer, Tobias Back, K. Sartor

The imaging of stroke has passed through major adjustments due to the fast development in imaging know-how. This quantity, comprising 3 components, is designed to supply a accomplished precis of the present function of MR imaging in sufferers with ischemic stroke. the 1st half outlines the scientific displays of stroke and discusses the diagnostic efficacy and healing influence of MR imaging. the second one and 3rd components shape the center of the quantity, and are in response to a singular procedure in that the subject is gifted from very diverse viewpoints. half 2 presents a close presentation of the distinguishing beneficial properties of stroke from the radiologist's point of view. in contrast, half three addresses the wishes of the clinician, documenting particular stroke syndromes and their correlates on MR imaging. the final goal has been to create a well-illustrated quantity with vast attraction that hyperlinks pathology, radiology and stroke drugs in an informative manner.

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By Rüdiger von Kummer, Tobias Back, K. Sartor

The imaging of stroke has passed through major adjustments due to the fast development in imaging know-how. This quantity, comprising 3 components, is designed to supply a accomplished precis of the present function of MR imaging in sufferers with ischemic stroke. the 1st half outlines the scientific displays of stroke and discusses the diagnostic efficacy and healing influence of MR imaging. the second one and 3rd components shape the center of the quantity, and are in response to a singular procedure in that the subject is gifted from very diverse viewpoints. half 2 presents a close presentation of the distinguishing beneficial properties of stroke from the radiologist's point of view. in contrast, half three addresses the wishes of the clinician, documenting particular stroke syndromes and their correlates on MR imaging. the final goal has been to create a well-illustrated quantity with vast attraction that hyperlinks pathology, radiology and stroke drugs in an informative manner.

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Extra resources for Book MRI in Ischemic Stroke

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2003; Read et al. 2000). There is mounting evidence that the time window for salvage of the penumbra is well beyond 3 h and multimodal MRI can identify such patients. The evolution of the mismatch model of the penumbra has led to a number of studies examining the response of acute DWI/PI patterns to thrombolytic therapy, particularly with respect to treatment beyond 3 h after stroke onset (Jansen et al. 1999; Kidwell et al. 2000; Parsons et al. 2002a; Schellinger et al. 2000). These studies supported the mismatch-penumbra hypothesis by demonstrating that thrombolysis rescues mismatch tissue from infarction.

2003; Read et al. 2000). There is mounting evidence that the time window for salvage of the penumbra is well beyond 3 h and multimodal MRI can identify such patients. The evolution of the mismatch model of the penumbra has led to a number of studies examining the response of acute DWI/PI patterns to thrombolytic therapy, particularly with respect to treatment beyond 3 h after stroke onset (Jansen et al. 1999; Kidwell et al. 2000; Parsons et al. 2002a; Schellinger et al. 2000). These studies supported the mismatch-penumbra hypothesis by demonstrating that thrombolysis rescues mismatch tissue from infarction.

Parsons and S. M. Davis Mean transit time delay (seconds) 30 15 10 5 0 2 4 Time to initial MRI (hours) 6 Fig. 8. Graph demonstrating that the perfusion threshold for mismatch tissue to be salvaged from infarction declines with time. These patients all had major reperfusion on follow-up imaging and tissue with severe hypoperfusion (mean transit time 15-s delay) was able to be salvaged from infarction within 3 h, but at 6 h, the threshold for salvage declined to only 3 s delay in mean transit time (Butcher et al.

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