Download Cell Mechanics: From Single Scale-Based Models to Multiscale by Arnaud Chauvière, Luigi Preziosi, Claude Verdier PDF

By Arnaud Chauvière, Luigi Preziosi, Claude Verdier

Ubiquitous and basic in mobile mechanics, multiscale difficulties can come up within the development of tumors, embryogenesis, tissue engineering, and extra. Cell Mechanics: From unmarried Scale-Based versions to Multiscale Modeling brings jointly new perception and study on mechanical, mathematical, actual, and organic techniques for simulating the habit of cells, in particular tumor cells.

In the 1st a part of the textual content, the publication discusses the robust software of microrheology for investigating phone mechanical houses, multiphysics and multiscale ways for learning intracellular mechanisms in phone motility, and the position of subcellular results concerning sure genes for inducing mobile motility in melanoma. concentrating on versions according to actual, mathematical, and computational methods, the second one part develops instruments for describing the complicated interaction of phone adhesion molecules and the dynamic evolution of the mobile cytoskeleton. The 3rd half explores cellphone interactions with the surroundings, rather the position of exterior mechanical forces and their results on phone habit. the ultimate half offers cutting edge versions of multicellular structures for developmental biology, melanoma, and embryogenesis.

This ebook collects novel ways to observe to cells and tissues via a multiscale strategy. It provides a number of present instruments whereas stimulating the invention of latest techniques which can result in more advantageous and actual predictions of pathologies.

Show description

By Arnaud Chauvière, Luigi Preziosi, Claude Verdier

Ubiquitous and basic in mobile mechanics, multiscale difficulties can come up within the development of tumors, embryogenesis, tissue engineering, and extra. Cell Mechanics: From unmarried Scale-Based versions to Multiscale Modeling brings jointly new perception and study on mechanical, mathematical, actual, and organic techniques for simulating the habit of cells, in particular tumor cells.

In the 1st a part of the textual content, the publication discusses the robust software of microrheology for investigating phone mechanical houses, multiphysics and multiscale ways for learning intracellular mechanisms in phone motility, and the position of subcellular results concerning sure genes for inducing mobile motility in melanoma. concentrating on versions according to actual, mathematical, and computational methods, the second one part develops instruments for describing the complicated interaction of phone adhesion molecules and the dynamic evolution of the mobile cytoskeleton. The 3rd half explores cellphone interactions with the surroundings, rather the position of exterior mechanical forces and their results on phone habit. the ultimate half offers cutting edge versions of multicellular structures for developmental biology, melanoma, and embryogenesis.

This ebook collects novel ways to observe to cells and tissues via a multiscale strategy. It provides a number of present instruments whereas stimulating the invention of latest techniques which can result in more advantageous and actual predictions of pathologies.

Show description

Read or Download Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling (Chapman & Hall CRC Mathematical & Computational Biology) PDF

Best biomedical engineering books

Protein Engineering and Design

The layout and construction of novel peptides and proteins occupy pivotal positions in technology and expertise and may proceed to take action within the twenty first century. Protein Engineering and layout outlines the fast advances in computer-based modeling, protein engineering, and techniques wanted for protein and peptide coaching and characterization.

Ambulatory Impedance Cardiography: The Systems and their Applications

”Ambulatory Impedance Cardiography” supplies the reader the required actual heritage of impedance cardiography (ICG) and at the moment to be had platforms for hemodynamics holter tracking. It compares ambulatory ICG and different clinically authorised equipment via an up to date state of the art. The booklet is split in four elements.

Bioinspired Approaches for Human-Centric Technologies

The current e-book discusses subject matters with regards to examine and improvement of fabrics and units at nanoscale measurement and their respective program in drugs and biomedicine. the person chapters provide a close cutting-edge evaluate to the distinctive subject. it seems that disconnected fields - existence sciences, biomedicine, chemistry, physics, medication and engineering - might be bridged with a hugely interdisciplinary view onto every one topic.

Bioprinting: Principles and Applications

At labs world wide, researchers were experimenting with bioprinting, first simply to see no matter if it used to be attainable to push cells via a printhead with no killing them (in such a lot instances it is), after which attempting to make cartilage, bone, dermis, blood vessels, small bits of liver and different tissues. There are alternative routes to aim to "engineer" tissue — one contains making a scaffold out of plastics or different fabrics and including cells to it.

Additional info for Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling (Chapman & Hall CRC Mathematical & Computational Biology)

Example text

J. Biomech. 33:127–135. [37] M. P. Theret, L. Wheeler, N. M. Nerem (1990). Application of the micropipette technique to the measurement of culture porcine aortic endothelial cell viscoelastic properties. J. Biomech. Eng. 112:263–268. [38] P. Sollich (1998). Rheological constitutive equation for a model of soft glassy materials. Phys. Rev. E 58:738–759. [39] O. Thoumine and A. Ott (1997). Time scale dependent viscoelastic and contractile regimes in fibroblasts probed by microplate manipulation. J.

Desprat, D. Icard, S. Fereol, A. Asnacios, J. Browaeys, S. Henon, and F. Gallet (2006). Power laws in microrheology experiments on living cells: comparative analysis and modeling. Phys. Rev. E 74:021911. 003 < t < 30 s, which exactly matches the experimental range of our measurements. This reinforces the validity of our approach. From the same analysis performed on our data on alveolar epithelial cells A549 we infer that the highest response time is ␶m ≈ 300 s for this type of cell. Other experiments [14] yield a typical time ␶m ≈ 3200 s.

Application of the micropipette technique to the measurement of culture porcine aortic endothelial cell viscoelastic properties. J. Biomech. Eng. 112:263–268. [38] P. Sollich (1998). Rheological constitutive equation for a model of soft glassy materials. Phys. Rev. E 58:738–759. [39] O. Thoumine and A. Ott (1997). Time scale dependent viscoelastic and contractile regimes in fibroblasts probed by microplate manipulation. J. Cell Sci. 110:2109–2116. [40] X. Trepat, M. Grabulosa, L. Buscemi, F. Rico, R.

Download PDF sample

Rated 4.53 of 5 – based on 28 votes