By Prasanti Babu, Anuj K. Chandel, Om V. Singh
Extremophiles are identified to thrive below harsh environmental stipulations. Many extremophilic bio-products are already used as life-saving medications. fresh technological developments of platforms biology have opened the door to discover those organisms anew as assets of goods that will turn out necessary in medical, environmental and drug development.
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Extra info for Extremophiles and Their Applications in Medical Processes
Wiley, Hoboken Acharya S, Chaudhary A (2012) Bioprospecting thermophiles for cellulose production: a review. Braz J Microbiol 43:844–856 Achterman RR, White TC (2011) Dermatophyte Virulence factors: identifying and analyzing genes that may contribute to chronic or acute skin infections. Int J Microbiol 2012:358305 Adams MW, Kelly RM (1998) Finding and using hyperthermophilic enzymes. Trends Biotechnol 16:329–332 Adams MWW (1993) Enzymes and proteins from organisms that grow near and above 100 °C.
2005), Arora et al. 1 (continued) Able to sense changes in temperatures: modulating membrane fluidity; leading bacteria to become temperature sensitive; aiding in establishing viral vaccinations; protecting against diseases that require cold-mediated immunity; increased enzyme production; lowering the temperature can change the flexibility of human proteins Acid proteinases, elastase, keratinases; antibiotic cells; cell mediated immune reactions: can rid the fungus from the skin; leukocytes; antibodies Changes in membrane fluidity; amounts of fatty acids; changes in biochemical processes; Pressure-sensing mechanisms/ organs: pressure-regulated operons Implications Marteinsson et al.
2014; Shin et al. 2014). Understanding of genetic roles in metabolic and regulatory networks lies ahead to grasping the functionality of biological system. Functional “-omics” consists of high-throughput global experimental approaches that make use of the information and reagents provided by structural genomics to assess gene function (Hieter and Boguski 1997). , mRNAs), proteomics (global proteins expression), and metabolomics (global expression of primary and secondary metabolites). Comprehensive transcriptome information for the extremophile Arabidopsis relative Thellungiella salsuginea provides ﬁrsthand clues of functional genomics elements in plant stress tolerance (Lee et al.