By Xiadou Wang, Jeffrey S. Nyman, Michael Reyes, Xuanliang Dong, Huijie Leng, K.A. Athanasiou
This eight-chapter monograph intends to provide simple rules and functions of biomechanics in bone tissue engineering so as to help tissue engineers in layout and use of tissue-engineered items for fix and substitute of damaged/deformed bone tissues. in short, bankruptcy 1 offers an total evaluate of biomechanics within the box of bone tissue engineering. bankruptcy 2 presents distinctive information about the composition and structure of bone. bankruptcy three discusses the present methodologies for mechanical trying out of bone homes (i.e., elastic, plastic, damage/fracture, viscoelastic/viscoplastic properties). bankruptcy four offers the present knowing of the mechanical habit of bone and the linked underlying mechanisms. bankruptcy five discusses the constitution and houses of scaffolds presently used for bone tissue engineering purposes. bankruptcy 6 provides a quick dialogue of present mechanical and structural checks of repair/tissue engineered bone tissues. bankruptcy 7 summarizes the houses of repair/tissue engineered bone tissues at the moment attained. ultimately, bankruptcy eight discusses the present concerns concerning biomechanics within the sector of bone tissue engineering. desk of Contents: advent / Bone Composition and constitution / present Mechanical try out Methodologies / Mechanical habit of Bone / constitution and houses of Scaffolds for Bone Tissue Regeneration / Mechanical and Structural evaluate of Repair/Tissue Engineered Bone / Mechanical and Structural homes of Tissues Engineered/Repair Bone / present problems with Biomechanics in Bone Tissue Engineering
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Additional resources for Fundamental Biomechanics in Bone Tissue Engineering (Synthesis Lectures on Tissue Engineering)
P. 21597–602. , Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. J Biol Chem, 1991. 266(18). p. 11654–60. , Effect of collagen turnover on the accumulation of advanced glycation end products. J Biol Chem, 2000. 275(50). p. 39027–31. , Advanced glycation end products and bone loss during aging. Ann N Y Acad Sci, 2005. 1043. p. 710–7. , Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links.
Therefore, bone material can be simplified as a two-phase composite. Thus, composite materials models can describe its mechanical behavior [43,44]. Bone can be treated as two-phase mixture in two different ways. One is to consider bone tissue as a composite of mineralized collagen fibers and organic matrix 22 2. 5: Illustration of bone composite model as a two-phase mixture. from the point view of structure. The other is to treat bone tissue as a composite of mineral and collagen from the point view of composition.
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