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By Basolo F. (ed.)

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Goldberg, Adelphi University Gregory V. Hartland, University of Notre Dame Ronald C. Johnson, Emory University Jeffrey Kovac, University of Tennessee John Z. Larese, University of Tennessee Joe March, University of Alabama at Birmingham Lyle V. McAfee, The Citadel David Miller, California State University, Northridge Wyatt R. , Seton Hall University Mary-Ann Pearsall, Drew University Vicente Talanquer, University of Arizona Wayne Tikkanen, California State University, Los Angeles Patricia Metthe Todebush, Northwestern University Copyright 2008 Thomson Learning, Inc.

3 Heating to a higher temperature causes further decomposition (charring) to carbon and water vapor. Chemical change. Heat can caramelize or char sugar. Copyright 2008 Thomson Learning, Inc. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. 13 © Thomson Learning/Charles D. Winters © Thomson Learning/Charles D. 6 Chemical change. Vinegar, which is an acid, has been added to an egg, causing colorless carbon dioxide gas to bubble away from the eggshell, which consists mainly of calcium carbonate.

May not be copied, scanned, or duplicated, in whole or in part. 3 4 Chapter 1 THE NATURE OF CHEMISTRY Letters are chemical symbols that represent atoms. Lines represent connections between atoms. H H H C C C C C C C N C C H C H H H H H H H C O H C C H The space occupied by each atom is more accurately represented in this model. C C O …and the three-dimensional arrangement of the atoms relative to one another. H C H To a chemist, molecular structure refers to the way the atoms in a molecule are connected together… O O Structural formula C H H Ball-and-stick model Space-filling model The molecular structure of one of the two molecular parts of paclitaxel used by Wall and Wani to determine the structure of the drug.

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