Download Natural Killer Cells by Eric Vivier, James Di Santo, Alessandro Moretta (eds.) PDF

By Eric Vivier, James Di Santo, Alessandro Moretta (eds.)

To have fun the fortieth anniversary of the invention of typical Killer (NK) cells, this quantity specializes in the new advances in our knowing of NK cellphone improvement and differentiation and their acquisition of sensible houses, in addition to the newest versions for NK-cell research in mice and purposes in scientific drugs. NK cells have travelled a circuitous direction from their preliminary description as ‘spontaneous killers’ (for a few easily an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of motion in immune security and an enormous mediator of immune reactivity in wellbeing and fitness and disorder. jointly, those reports offer a well timed and concise photo of the evolution of NK cells as crucial brokers in immunity and as powerful guns opposed to affliction. This ebook deals an beautiful and insightful source for scientists and clinicians.

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By Eric Vivier, James Di Santo, Alessandro Moretta (eds.)

To have fun the fortieth anniversary of the invention of typical Killer (NK) cells, this quantity specializes in the new advances in our knowing of NK cellphone improvement and differentiation and their acquisition of sensible houses, in addition to the newest versions for NK-cell research in mice and purposes in scientific drugs. NK cells have travelled a circuitous direction from their preliminary description as ‘spontaneous killers’ (for a few easily an experimental artifact) to being a bona fide subset of innate lymphoid cells with a complementary mode of motion in immune security and an enormous mediator of immune reactivity in wellbeing and fitness and disorder. jointly, those reports offer a well timed and concise photo of the evolution of NK cells as crucial brokers in immunity and as powerful guns opposed to affliction. This ebook deals an beautiful and insightful source for scientists and clinicians.

Show description

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Additional resources for Natural Killer Cells

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J Biol Chem 287:7324–7334 Lanier LL (2008) Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 9:495–502 Lee CK, Rao DT, Gertner R, Gimeno R, Frey AB, Levy DE (2000) Distinct requirements for IFNs and STAT1 in NK cell function. J Immunol 165:3571–3577 Lee JS, Cella M, McDonald KG, Garlanda C, Kennedy GD, Nukaya M, Mantovani A, Kopan R, Bradfield CA, Newberry RD et al (2012) AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch.

J Exp Med 186:1597–1602 Held W, Kunz B, Lowin-Kropf B, van de Wetering M, Clevers H (1999) Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1. Immunity 11:433–442 Held W, Clevers H, Grosschedl R (2003) Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition. Eur J Immunol 33:1393–1398 Hess Michelini R, Doedens AL, Goldrath AW, Hedrick SM (2013) Differentiation of CD8 memory T cells depends on Foxo1.

Immunity 17:117–130 Ikawa T, Kawamoto H, Fujimoto S, Katsura Y (1999) Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med 190:1617–1626 Ikawa T, Fujimoto S, Kawamoto H, Katsura Y, Yokota Y (2001) Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2. Proc Natl Acad Sci USA 98:5164–5169 Ikawa T, Hirose S, Masuda K, Kakugawa K, Satoh R, Shibano-Satoh A, Kominami R, Katsura Y, Kawamoto H (2010) An essential developmental checkpoint for production of the T cell lineage.

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