Download Red Blood Cell Alloimmunization after Blood Transfusion (LUP by H. Schonewille PDF

By H. Schonewille

Present pre-transfusion coverage calls for the sufferers' serum to be validated for the presence of abnormal purple blood mobile antibodies. In case of an alloantibody, crimson blood cells missing the corresponding antigen are transfused after an antiglobulin crossmatch. the purpose of the stories during this thesis is essentially to enquire even if this coverage may still switch to enhance transfusion defense. This thesis explores the danger on pink blood mobile alloimmunization after blood transfusion in oncohematologic sufferers and in sufferers who already shaped antibodies after a prior transfusion occasion. moreover, the dangers of present pretransfusion trying out in regards to antibodies to low prevalence antigens, timing of antibody checking out and antibody patience have been studied.

Show description

By H. Schonewille

Present pre-transfusion coverage calls for the sufferers' serum to be validated for the presence of abnormal purple blood mobile antibodies. In case of an alloantibody, crimson blood cells missing the corresponding antigen are transfused after an antiglobulin crossmatch. the purpose of the stories during this thesis is essentially to enquire even if this coverage may still switch to enhance transfusion defense. This thesis explores the danger on pink blood mobile alloimmunization after blood transfusion in oncohematologic sufferers and in sufferers who already shaped antibodies after a prior transfusion occasion. moreover, the dangers of present pretransfusion trying out in regards to antibodies to low prevalence antigens, timing of antibody checking out and antibody patience have been studied.

Show description

Read Online or Download Red Blood Cell Alloimmunization after Blood Transfusion (LUP Dissertations) PDF

Best microbiology books

Advanced Physicochemical Treatment Technologies: Volume 5 (Handbook of Environmental Engineering)

In complex Physiochemical remedy applied sciences, top toxins keep watch over educators and training execs describe how a number of combos of other state-of-the-art approach structures may be prepared to resolve air, noise, and thermal pollutants difficulties. each one bankruptcy discusses intimately the 3 uncomplicated kinds during which toxins and waste are manifested: gasoline, stable, and liquid.

Carotenoids in health and disease

The 1st resource to assemble the most recent facts linking carotenoids to human health and wellbeing and illness, this stimulating reference reports the function of carotenoids within the prevention of power illness and experiences leap forward experiences from greater than forty box experts at the most recent study. The ebook unearths the newest findings in regards to the use of carotenoids within the prevention of cancers and sunburn, in addition to eye, center, vascular, and photosensitivity illnesses, and evaluates the aptitude poisonous results of high-dose carotenoids in either people who smoke and drinkers.

Hydrocarbon and Lipid Microbiology Protocols: Petroleum, Hydrocarbon and Lipid Analysis

This quantity provides equipment for analysing and quantifying petroleum, hydrocarbons and lipids, in response to their chemical and actual houses in addition to their organic results. It beneficial properties protocols for extracting hydrocarbons from reliable matrices, water and air, and a committed bankruptcy concentrating on unstable natural compounds.

Additional info for Red Blood Cell Alloimmunization after Blood Transfusion (LUP Dissertations)

Sample text

Rev. Immunol. 1987;5:585-620 Tonegawa S. Somatic generation of antibody diversity. Nature 1983;302:575-581 Clark EA, Ledbetter JA. How B and T cells talk to each other. Nature 1994;367:425-428 Jenkins MK. The ups and downs of T cell costimulation. Immunity 1994;1:443-446 Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med. 1995;182:459-65 Peggs KS, Allison JP. Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily.

Ness PM, Shirey RS, Thoman SK, Buck SA. The differentiation of delayed serologic and delayed hemolytic transfusion reactions: incidence, long-term serologic findings, and clinical significance. Transfusion 1990;30:688-693 Vamvakas EC, Pineda AA, Reisner R, Santrach PJ, Moore SB. The differentiation of delayed hemolytic and delayed serologic transfusion reactions: incidence and predictors of hemolysis. Transfusion 1995;35:26-32 Pineda AA, Vamvakas EC, Gordon LD, Winters JL, Moore SB. Trends in the incidence of delayed hemolytic and delayed serologic transfusion reactions.

Oncol. 1999;21:224-230 Strauss RG, Johnson K, Cress G, Cordle DG. Alloimmunization in preterm infants after repeated transfusions of WBC-reduced RBCs from the same donor. Transfusion 2000;40:1463-1468 3 ALLOIMMUNIZATION TO RED BLOOD CELL ANTIGENS AFTER UNIVERSAL LEUCODEPLETION. A REGIONAL MULTICENTRE RETROSPECTIVE STUDY ` Henk Schonewille, Anneke Brand. Alloimmunization to red blood cell antigens after universal leucodepletion. A regional multicenter study. Brit. J. Haematol. 2005;129:151-156 Chapter 3 SUMMARY Leucodepletion has shown to reduce human leucocyte antigen immunization, but studies on the effect of leucodepletion on red cell alloimmunization reported discordant results.

Download PDF sample

Rated 4.89 of 5 – based on 27 votes