Download The Blood-Brain Barrier: Biology and Research Protocols by Sukriti Nag PDF

By Sukriti Nag

A first-time selection of state-of-the-art morphologic, permeability, shipping, in vitro, and molecular options to check the workings of the blood-brain barrier in healthiness and illness. defined in step by step aspect, each one easily reproducible strategy contains a proof of the theoretical foundation of the tactic, a dialogue of its benefits and barriers, notes on fending off pitfalls, and examples of effects acquired utilizing the technqiue. those robust instruments can be utilized to isolate undiscovered molecules, deepen our figuring out in their position in wellbeing and fitness and sickness, and establish objectives for destiny gene remedy and healing intervention.

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By Sukriti Nag

A first-time selection of state-of-the-art morphologic, permeability, shipping, in vitro, and molecular options to check the workings of the blood-brain barrier in healthiness and illness. defined in step by step aspect, each one easily reproducible strategy contains a proof of the theoretical foundation of the tactic, a dialogue of its benefits and barriers, notes on fending off pitfalls, and examples of effects acquired utilizing the technqiue. those robust instruments can be utilized to isolate undiscovered molecules, deepen our figuring out in their position in wellbeing and fitness and sickness, and establish objectives for destiny gene remedy and healing intervention.

Show description

Read or Download The Blood-Brain Barrier: Biology and Research Protocols (Methods in Molecular Medicine) PDF

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1989) Brain capillary 46,000 Dalton protein is cytoplasmic actin and is localized to endothelial plasma membrane. J. Cereb. Blood Flow Metab. 9, 675–680. 102. , Parkos, C. , et al. (2000) Tight junctions are membrane microdomains. J. Cell Sci. 113, 1771–1781. 103. , and Lisanti, M. P. (2001) The caveolin triad: caveolae biogenesis, cholesterol trafficking, and signal transduction. Cytokine Growth Factor Rev. 12, 41–51. 104. Madara, J. , and Kaoutzani, P. (1992) The movement of solutes and cells across tight junctions.

36. Stewart, P. , and Wiley, M. J. (1981) Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail-chick transplantation chimeras. Dev. Biol. 84, 183–192. 37. , and Risau, W. (1992) Expression of vascular endothelial growth-factor during embryonic angiogenesis and endothelial-cell differentiation. Development 114, 521–532. 38. , Escobedo, J. , and Williams, L. T. (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth-factor.

295, 77–88. 179. , Todd, R. F. , and Dore-Duffy, P. (1994) Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis. Ann. Neurol. 35, 89–97. 180. Williams, K. , Zhao, R. , and Hickey, W. F. (1996) PECAM-1 (CD31) expression in the central nervous system and its role in experimental allergic encephalomyelitis in the rat. J. Neurosci. Res. 45, 747–757. 181. , and Dorovini-Zis, K. (1996) Regulation by cytokines and lipopolysaccharide of E-selectin expression by human brain microvessel endothelial cells in primary culture.

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