By Bernhard Palsson; et al
Content material: part I. PHYSIOLOGIC platforms -- advent / Robert Plonsey -- define of cardiovascular constitution and serve as / Daniel J. Schneck -- Endocrine process / Derek G. Cramp, Ewart R. Carson -- frightened method / Evangelia Micheli-Tzanakou -- imaginative and prescient process / George Stetten -- Auditory process / Ben M. CLopton, Francis A. Spelman -- Gastrointestinal approach / Berj L. Bardakjian -- breathing approach / Arthur T. Johnson, Christopher G. Lausted, Joseph D. Bronzino -- part II. TISSUE ENGINEERING -- creation / Bernhard Ø. Palsson, Jeffrey A. Hubbell -- basics of tissue engineering / François Berthiaume, Martin L. Yarmush -- floor immobilization of adhesion ligands for investigations of cell-substrate interactions / Paul D. Drumheller, Jeffrey A. Hubbell -- Biomaterials: protein-surface interactions / Joseph A. Chin, Steven M. Slack -- Engineering biomaterials for tissue engineering: the 10-100 micron measurement scale / David J. Mooney, Robert S. Langer -- Fluid shear pressure results on mobile functionality / Charles W. Patrick, Jr., Rangarajan Sampath, Larry V. McIntire -- Roles of mass move in tissue functionality / Edwin N. Lightfoot, Karen A. Duca -- Biology of stem cells / Craig T. Jordan, Gary Van Zant -- phone motility and tissue structure / Graham A. Dunn -- Tissue microenvironments / Michael W. lengthy -- significance of stromal cells / Brian A. Naughton -- Tissue engineering of bone marrow / Manfred R. Koller, Bernhard Ø. Palsson -- Tissue engineering of the liver / Tae Ho Kim, Joseph P. Vacanti -- Tissue engineering within the anxious procedure / Ravi Bellamkonda, Patrick Aebischer -- Tissue engineering of skeletal muscle / Susan V. Brooks, John A. Faulkner -- Tissue engineering of cartilage / L.E. Freed, G. Vunjak-Novakovic -- Tissue engineering of the kidney / H. David Humes
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If the response lasts longer than the interval between impulses, such that the second response rises from the residue of the first, then it is temporal summation. If, in addition, the response increment due to the second stimulus is larger than the preceding one, then it is facilitation. Facilitation is an important function of the nervous system and is found in quite different forms and durations ranging from a few milliseconds to tenths of seconds. Facilitation may grade from forms of sensitization to learning, especially at long intervals.
Since what is communicated is nothing more than impulses — spike trains — the only basic variables in a train of events are the number and intervals between spikes. With respect to this, the nervous system acts like a pulse-coded analog device, since the intervals are continuously graded. There exists a distribution of interval lengths between individual spikes, which in any sample can be expressed by the shape of the interval histogram. If one examines different examples, their distributions differ markedly.
If one examines different examples, their distributions differ markedly. Some histograms look like Poisson distributions; some others exhibit Gaussian or bimodal shapes. The coefficient of variation — expressed as the standard deviation over the mean — in some cases is constant, while in others it varies. Some other properties depend on the sequence of longer and shorter intervals than the mean. Some neurons show no linear dependence; some others show positive or negative correlations of successive intervals.